You should treat cleaning as routine maintenance, not something you only do after a spill. The guide recommends a regular cycle of cleaning and maintenance every ten to fifteen runs, and at least weekly, because residues and moisture build up quietly and then cause corrosion, odours, and performance issues.
How often should you clean your centrifuge, and what should you never do?

The “never do” list matters more than people think. Do not pour liquid into the centrifuge housing and do not spray disinfectant directly into the device, because liquid can reach areas that are not meant to get wet and cause damage. Power down first and disconnect before you start. Clean using a cloth and a suitable agent, then dry everything fully before reconnecting.
On cleaning chemicals, the guide is clear that you should use a pH-neutral detergent (pH is a measure of acidity and alkalinity) in the range pH 6 to pH 8, because aggressive or alkaline products accelerate corrosion on anodised parts. Drying can be helped with gentle warmth, but keep within the guide’s stated temperature limit.
If you want the exact step-by-step method for the centrifuge, chamber, and accessories, download the full Centrifuge and Rotor Maintenance and Cleaning Guide.

